SPYRE THERAPEUTICS INC
SYRENASDAQ🏆 #1037 by market capEarnings Nov 3US Equity
$84.72▼ $1.06 (−1.25%)
🌙 After hours$83.89▼ 0.98%Regular close · extended-hours price shownTrack SYRE
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24h▼ 1.3%
7d▼ 7.9%
14d▼ 6.9%
30d▼ 6.3%
ytd▲ 158.6%
1y▲ 416.9%
🏦Market Cap
$7.36B
Small Cap
📈Revenue Growth (YoY)
—
📊Gross Margin
—
💵FCF Margin
—
⚖️P/S Ratio
6185.8x
Expensive
Otter Score
44
Weak
SPYRE THERAPEUTICS INC
SYREAnalyst Ratings
Price
$84.72
Total
13
Raised
0
Lowered
1
Avg PT
$111.82
H / L
$130 / $80
| Institution | Action | Rating | Date | Upside | |
|---|---|---|---|---|---|
Wedbush | Reiterated | Outperform | 2026-09-09 | $123.00 | +45.20% |
BTIG | Reiterated | Buy | 2026-09-08 | $121.00 | +42.80% |
Deutsche Bank | Reiterated | Buy | 2026-08-26 | $127.00 | +49.90% |
Wells Fargo | Reiterated | Overweight | 2026-08-05 | $115.00 | +35.70% |
Guggenheim | Reiterated | Buy | 2026-08-05 | $130.00 | +53.40% |
Wolfe Research | Downgraded | Outperform → Peer Perform | 2026-07-28 | — | — |
Mizuho | Reiterated | Outperform | 2026-07-13 | — | — |
Citigroup | Reiterated | Buy | 2026-05-06 | — | — |
Stifel | Reiterated | Buy | 2026-05-06 | — | — |
Jones Trading | Reiterated | Buy | 2026-04-17 | — | — |
Baird | Reiterated | Outperform | 2026-04-14 | — | — |
Leerink Partners | Reiterated | Outperform | 2026-04-13 | $106.00 | +25.10% |
Jefferies | Reiterated | Buy | 2026-04-13 | $85.00 | +0.30% |
Institution
Wedbush
Reiterated · Outperform · 2026-09-09
$123.00
+45.20%
BTIG
Reiterated · Buy · 2026-09-08
$121.00
+42.80%
Deutsche Bank
Reiterated · Buy · 2026-08-26
$127.00
+49.90%
Wells Fargo
Reiterated · Overweight · 2026-08-05
$115.00
+35.70%
Guggenheim
Reiterated · Buy · 2026-08-05
$130.00
+53.40%
Wolfe Research
Downgraded · Outperform → Peer Perform · 2026-07-28
—
—
Mizuho
Reiterated · Outperform · 2026-07-13
—
—
Citigroup
Reiterated · Buy · 2026-05-06
—
—
Stifel
Reiterated · Buy · 2026-05-06
—
—
Jones Trading
Reiterated · Buy · 2026-04-17
—
—
Baird
Reiterated · Outperform · 2026-04-14
—
—
Leerink Partners
Reiterated · Outperform · 2026-04-13
$106.00
+25.10%
Jefferies
Reiterated · Buy · 2026-04-13
$85.00
+0.30%
One row per institution · price target from the firm's latest published target