STOK logo

STOKE THERAPEUTICS INC

STOKNASDAQ
πŸ† #2138 by market capEarnings Nov 2US Equity
$25.88β–² $0.39 (+1.49%)
πŸŒ™ After hours$25.88β–² 0.00%Regular close Β· extended-hours price shown
πŸ””
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24hβ–² 1.5%
7dβ–Ό 11.4%
14dβ–Ό 8.1%
30dβ–Ό 18.1%
ytdβ–Ό 18.4%
1yβ–² 4.8%
🏦Market Cap
$1.67B
Small Cap
πŸ“ˆRevenue Growth (YoY)
+404.5%
High Growth
πŸ“ŠGross Margin
84.7%
High
πŸ’΅FCF Margin
-654.9%
Thin
βš–οΈP/S Ratio
59.6x
Expensive
Otter Score
68
Fair

Trading Snapshot

Day Range
$25.50 – $26.12
52-Week Range
$20.32 – $40.22
Volume
$5.10B
Avg Volume
$6.27B
Shares Outstanding
64.5M
Next Earnings
Oct 29, 2026

Fundamentals Snapshot

Annual Revenue
$184M
Last Q Revenue
$9M
P/E Ratio
-7.6
P/S Ratio
59.6x
EPS (TTM)
$-3.15
Dividend Yield
0.00%
Dilution (1yr)
+2.4%

Why Investors Own STOK

  • βœ“High-growth profile β€” revenue up -1.8% YoY with expanding US Equity exposure.
  • βœ“Healthy economics β€” 58% gross margin and 11% free-cash-flow margin.
  • βœ“New products and segments could unlock additional revenue streams.
⚠️ Key Risks

Execution delays, intensifying competition, and valuation compression if growth decelerates.

STOK logo

STOKE THERAPEUTICS INC

STOK
Financial Trends
RevenueThe total money the company brought in from sales, before subtracting any costs.
$184Mβ–² +404.5% YoY
Gross MarginOf every $1 of sales, how much is left after the direct cost of making the product/service. Higher = more efficient.
100.0%β–² +0.0% YoY
Operating IncomeProfit from the core business after operating costs, but before interest and taxes. Negative means the core business isn’t profitable yet.
βˆ’$21Mβ–Ό βˆ’79.7% YoY
Free Cash FlowCash left over after running the business and paying for equipment/capex. Negative means the company is burning cash.
$45Mβ–Ό βˆ’151.6% YoY
Shares OutstandingHow many shares exist. Rising means the company is issuing more shares, which dilutes (shrinks) each existing owner’s slice.
58.4Mβ–² +2.4% YoY
Net CashCash minus total debt. Positive = more cash than debt (financially strong); negative = more debt than cash (net debt).
$81Mβ–Ό βˆ’$42M YoY
StockOtter Β· stockotter.space

About STOKE THERAPEUTICS INC

Stoke Therapeutics, Inc. is an emerging biopharmaceutical company dedicated to developing innovative antisense oligonucleotide (ASO) therapies. Its primary focus is to target and address the fundamental causes of severe genetic disorders, particularly within the United States. The company employs its exclusive Targeted Augmentation of Nuclear Gene Output (TANGO) platform to engineer ASOs that precisely enhance protein expression. Stoke's most advanced candidate, STK-001, is currently progressing through Phase I/IIa clinical trials for Dravet syndrome, a severe and debilitating genetic epilepsy. Additionally, STK-002 is in the preclinical development stage for treating autosomal dominant optic atrophy. The company has also established a licensing and collaborative agreement with Acadia Pharmaceuticals Inc. to identify, develop, and market new RNA-based medicines for critical and rare genetic neurodevelopmental conditions impacting the central nervous system. Formerly known as ASOthera Pharmaceuticals, Inc., the company rebranded to Stoke Therapeutics, Inc. in May 2016. Founded in 2014, Stoke Therapeutics, Inc. maintains its headquarters in Bedford, Massachusetts.

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Otter Score Breakdown

How it's scoredFive components, each rated 1–5β˜… and equally weighted (20%), averaged to a 0–100 score:πŸ’Ž Quality β€” gross marginπŸš€ Growth β€” revenue YoYβš–οΈ Valuation β€” P/S ratio⚑ Momentum β€” 30-day price changeπŸ’§ Dilution β€” 1-yr share issuance (buybacks score higher)
πŸ’ŽQualityβ˜…β˜…β˜…β˜…β˜…
πŸš€Growthβ˜…β˜…β˜…β˜…β˜…
βš–οΈValuationβ˜…β˜…β˜…β˜…β˜…
⚑Momentumβ˜…β˜…β˜…β˜…β˜…
πŸ’§Dilutionβ˜…β˜…β˜…β˜…β˜…
Overall Score
Fair
68/100

Analyst Ratings

β“˜
Consensus
Buy
20 analysts
Strong Buy8
Buy11
Hold1
Sell0
Strong Sell0
Ratings as of Sep 2026

Latest News & Updates

Defense WorldΒ·1d ago

Stoke Therapeutics, Inc. $STOK Shares Newly Acquired by Corient Private Wealth LP

Corient Private Wealth LP purchased a new stake in Stoke Therapeutics, Inc. (NASDAQ: STOK) during the second quarter, according to its most recent Form 13F filing with the SEC. The fund purchased 30,823 shares of the com

Business WireΒ·6d ago

Stoke Therapeutics Appoints Bo Cumbo to its Board of Directors, Enhancing Commercial Expertise as the Company Advances Zorevunersen Development Toward Potential FDA Approval and Commercialization

BEDFORD, Mass.--(BUSINESS WIRE)--Stoke Therapeutics, Inc. (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine and has a lead investigat

Defense WorldΒ·11d ago

Squarepoint Ops LLC Acquires Shares of 29,310 Stoke Therapeutics, Inc. $STOK

Squarepoint Ops LLC acquired a new position in Stoke Therapeutics, Inc. (NASDAQ: STOK) in the second quarter, according to its most recent Form 13F filing with the Securities and Exchange Commission. The firm acquired 29

Business WireΒ·13d ago

Stoke Therapeutics Announces Inducement Grants Under Nasdaq Listing Rule 5635(C)(4)

BEDFORD, Mass.--(BUSINESS WIRE)--Stoke Therapeutics, Inc. (Nasdaq: STOK) is a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine and has a lead investigat

GuruFocusΒ·26d ago

Stoke Therapeutics and Biogen Present Long-Term Clinical Data that Support the Disease-Modifying Potential of Zorevunersen, an Investigational Medicine for the Treatment of Dravet Syndrome, at the 16t

[url="]Stoke Therapeutics, Inc.[/url] (Nasdaq: STOK), a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with

Business WireΒ·26d ago

Stoke Therapeutics and Biogen Present Long-Term Clinical Data that Support the Disease-Modifying Potential of Zorevunersen, an Investigational Medicine for the Treatment of Dravet Syndrome, at the 16th European Epilepsy Congress (EEC)

BEDFORD, Mass. & CAMBRIDGE, Mass.--(BUSINESS WIRE)--Stoke Therapeutics, Inc. (Nasdaq: STOK), a biotechnology company dedicated to restoring protein expression by harnessing the body's potential with RNA medicine, and Bio