PYXS logo

PYXIS ONCOLOGY INC

PYXSNASDAQ
πŸ† #3769 by market capEarnings Nov 2 Β· PreUS Equity
$2.90β–² $0.00 (+0.00%)
πŸŒ… Pre-market$2.63β–Ό 9.31%Regular close Β· extended-hours price shown
πŸ””
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24hβ–² 0.0%
7dβ–Ό 9.9%
14dβ–Ό 13.3%
30dβ–Ό 10.5%
ytdβ–² 151.1%
1yβ–² 30.9%
🏦Market Cap
$184M
Small Cap
πŸ“ˆRevenue Growth (YoY)
-14.2%
Declining
πŸ“ŠGross Margin
99.8%
High
πŸ’΅FCF Margin
-615.3%
Thin
βš–οΈP/S Ratio
16.6x
Expensive
Otter Score
76
Good

Trading Snapshot

Day Range
$2.88 – $2.92
52-Week Range
$1.03 – $5.55
Volume
$2.54B
Avg Volume
$2.02B
Shares Outstanding
63.4M
Next Earnings
Dec 8, 2026

Fundamentals Snapshot

Annual Revenue
$14M
Last Q Revenue
$4M
P/E Ratio
-2.1
P/S Ratio
16.6x
EPS (TTM)
$-1.39
Dividend Yield
0.00%
Dilution (1yr)
+2.4%

Why Investors Own PYXS

  • βœ“High-growth profile β€” revenue up +16.6% YoY with expanding US Equity exposure.
  • βœ“Healthy economics β€” 76% gross margin and 23% free-cash-flow margin.
  • βœ“New products and segments could unlock additional revenue streams.
⚠️ Key Risks

Execution delays, intensifying competition, and valuation compression if growth decelerates.

PYXS logo

PYXIS ONCOLOGY INC

PYXS
Financial Trends
RevenueThe total money the company brought in from sales, before subtracting any costs.
$14Mβ–Ό βˆ’14.2% YoY
Gross MarginOf every $1 of sales, how much is left after the direct cost of making the product/service. Higher = more efficient.
82.8%β–Ό βˆ’14.7% YoY
Operating IncomeProfit from the core business after operating costs, but before interest and taxes. Negative means the core business isn’t profitable yet.
βˆ’$84Mβ–Ό βˆ’5.6% YoY
Free Cash FlowCash left over after running the business and paying for equipment/capex. Negative means the company is burning cash.
βˆ’$64Mβ–² +9.7% YoY
Shares OutstandingHow many shares exist. Rising means the company is issuing more shares, which dilutes (shrinks) each existing owner’s slice.
62.1Mβ–² +2.4% YoY
Net CashCash minus total debt. Positive = more cash than debt (financially strong); negative = more debt than cash (net debt).
βˆ’$3Mβ–Ό βˆ’$3M YoY
StockOtter Β· stockotter.space

About PYXIS ONCOLOGY INC

Pyxis Oncology, Inc. operates as a preclinical biopharmaceutical company focused on developing novel therapeutic approaches to combat various forms of cancer. Its investigational immune-oncology pipeline includes PYX-106, a fully human immunoglobulin G1 (IgG1) antibody designed to target siglec-15, which is being explored for its potential efficacy against thyroid cancer, head and neck squamous cell carcinoma, non-small cell lung cancer (NSCLC), and other solid tumors. Additionally, PYX-102 is an immune-therapeutic currently under investigation for the treatment of solid tumors. The company's portfolio also features a range of investigational antibody-drug conjugate (ADC) candidates: PYX-201, a novel ADC being developed for NSCLC, breast cancer, and other solid tumors; PYX-202, another novel ADC aimed at small cell lung cancer (SCLC), soft tissue sarcoma, and other solid tumors; and PYX-203, an ADC undergoing evaluation for acute myeloid leukemia and myeloid dysplastic syndrome. Pyxis Oncology was founded in 2018 and is based in Cambridge, Massachusetts.

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Otter Score Breakdown

How it's scoredFive components, each rated 1–5β˜… and equally weighted (20%), averaged to a 0–100 score:πŸ’Ž Quality β€” gross marginπŸš€ Growth β€” revenue YoYβš–οΈ Valuation β€” P/S ratio⚑ Momentum β€” 30-day price changeπŸ’§ Dilution β€” 1-yr share issuance (buybacks score higher)
πŸ’ŽQualityβ˜…β˜…β˜…β˜…β˜…
πŸš€Growthβ˜…β˜…β˜…β˜…β˜…
βš–οΈValuationβ˜…β˜…β˜…β˜…β˜…
⚑Momentumβ˜…β˜…β˜…β˜…β˜…
πŸ’§Dilutionβ˜…β˜…β˜…β˜…β˜…
Overall Score
Good
76/100

Analyst Price Target

β“˜
Average Target
$3.07
β–² +5.8% Upside
High Target$3.48
Low Target$2.35
Based on 23 analysts

Latest News & Updates

GlobeNewsWireΒ·10h ago

Pyxis Oncology Announces Pricing of Up to $282.6 Million Public Offering

BOSTON, Sept. 30, 2026 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced the pricing of its previous

GlobeNewsWireΒ·19h ago

Pyxis Oncology Announces Proposed Public Offering

BOSTON, Sept. 29, 2026 (GLOBE NEWSWIRE) -- Pyxis Oncology, Inc. (Nasdaq: PYXS), a clinical-stage company developing next-generation therapeutics for difficult-to-treat cancers, today announced that it has commenced a reg

Defense WorldΒ·9d ago

Critical Analysis: Pyxis Oncology (NASDAQ:PYXS) vs. ProKidney (NASDAQ:PROK)

ProKidney (NASDAQ: PROK - Get Free Report) and Pyxis Oncology (NASDAQ: PYXS - Get Free Report) are both small-cap healthcare companies, but which is the better stock? We will compare the two businesses based on the stren

Defense WorldΒ·14d ago

Alumis (NASDAQ:ALMS) & Pyxis Oncology (NASDAQ:PYXS) Head-To-Head Review

Pyxis Oncology (NASDAQ: PYXS - Get Free Report) and Alumis (NASDAQ: ALMS - Get Free Report) are both small-cap healthcare companies, but which is the superior investment? We will compare the two businesses based on the s

Seeking AlphaΒ·20d ago

Pyxis Oncology, Inc. (PYXS) Discusses MICVO Monotherapy Phase I Clinical Data in Head and Neck Squamous Cell Carcinoma Transcript

Pyxis Oncology, Inc. (PYXS) Discusses MICVO Monotherapy Phase I Clinical Data in Head and Neck Squamous Cell Carcinoma Transcript

BenzingaΒ·20d ago

Pyxis Oncology Analyst Flags Key Safety Liabilities from Cancer Drug

Pyxis Oncology Inc. (NASDAQ:PYXS) on Wednesday shared updated data from its Phase 1 trial evaluating micvotabart pelidotin (MICVO).