PROTHENA CORP PLC
PRTANASDAQTrading Snapshot
- Day Range
- $8.73 β $8.94
- 52-Week Range
- $7.73 β $11.80
- Volume
- $3.18B
- Avg Volume
- $2.51B
- Shares Outstanding
- 52.4M
- Next Earnings
- Dec 3, 2026
Fundamentals Snapshot
- Annual Revenue
- $10M
- Last Q Revenue
- $1M
- P/E Ratio
- β
- P/S Ratio
- 7.8x
- EPS (TTM)
- $-0.83
- Dividend Yield
- β
- Dilution (1yr)
- +0.0%
Why Investors Own PRTA
- βHigh-growth profile β revenue up +54.8% YoY with expanding US Equity exposure.
- βHealthy economics β 49% gross margin and 12% free-cash-flow margin.
- βNew products and segments could unlock additional revenue streams.
Execution delays, intensifying competition, and valuation compression if growth decelerates.
PROTHENA CORP PLC
PRTAAbout PROTHENA CORP PLC
Prothena Corporation plc, a late-stage clinical biotechnology company, focuses on discovery and development of novel therapies to treat diseases caused by protein dysregulation. Its product pipeline includes Prasinezumab, an investigational humanized monoclonal antibody which is in Phase 3 clinical trial for the treatment of parkinson's disease and other synucleinopathies. The company also develops Coramitug, an investigational antibody, which is in Phase 3 clinical trial for the treatment of transthyretin amyloidosis; BMS-986446, an anti-tau antibody which is in Phase 2 clinical trial to treat Alzheimer's disease; PRX019, an investigational antibody which is in Phase 1 clinical trial for the treatment of neurodegenerative diseases; and PRX123, a Dual AΓ-Tau Vaccine, which is in preclinical trial for treating Alzheimer's disease. In addition, it develops discovery- and late-preclinical-stage programs include TDP-43 CYTOPE for the treatment of amyotrophic lateral sclerosis; PRX012, a next-generation anti-AΓ antibody which is in phase 1 clinical trial to treat Alzheimer's disease; and PRX012-TfR, a preclinical program for the treatment of Alzheimer's disease. It has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target a-synuclein, including prasinezumab; and master collaboration agreement with Bristol Myers Squibb to develop and commercialize antibodies targeting tau, TDP-43. Prothena Corporation plc was incorporated in 2012 and is based in Dublin, Ireland.
Otter Score Breakdown
How it's scoredFive components, each rated 1β5β and equally weighted (20%), averaged to a 0β100 score:π Quality β gross marginπ Growth β revenue YoYβοΈ Valuation β P/S ratioβ‘ Momentum β 30-day price changeπ§ Dilution β 1-yr share issuance (buybacks score higher)Analyst Price Target
βLatest News & Updates

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PRTA's Q2 Loss Narrower Than Expected, Pipeline Progress in Focus
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Prothena (PRTA) Reports Q2 Loss, Misses Revenue Estimates
Prothena (PRTA) came out with a quarterly loss of $0.32 per share versus the Zacks Consensus Estimate of a loss of $0.39. This compares to a loss of $1.86 per share a year ago.