APRE logo

APREA THERAPEUTICS INC

APRENASDAQ
πŸ† #5030 by market capEarnings Nov 10US Equity
$0.77β–² $0.02 (+2.37%)
πŸŒ™ After hours$0.75β–Ό 2.53%Regular close Β· extended-hours price shown
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24hβ–² 2.4%
7dβ–² 6.9%
14dβ–² 0.8%
30dβ–Ό 8.2%
ytdβ–Ό 9.8%
1yβ–Ό 49.5%
🏦Market Cap
$10M
Small Cap
πŸ“ˆRevenue Growth (YoY)
-100.0%
Declining
πŸ“ŠGross Margin
0.0%
Thin
πŸ’΅FCF Margin
0.0%
Thin
βš–οΈP/S Ratio
0.0x
Cheap
Otter Score
56
Weak

Trading Snapshot

Day Range
$0.76 – $0.78
52-Week Range
$0.55 – $1.69
Volume
$2.24B
Avg Volume
$1.73B
Shares Outstanding
12.4M
Next Earnings
Nov 4, 2026

Fundamentals Snapshot

Annual Revenue
$3M
Last Q Revenue
$600,076
P/E Ratio
-0.6
P/S Ratio
0.0x
EPS (TTM)
$-0.23
Dividend Yield
0.00%
Dilution (1yr)
+29.1%

Why Investors Own APRE

  • βœ“High-growth profile β€” revenue up -7.5% YoY with expanding US Equity exposure.
  • βœ“Healthy economics β€” 32% gross margin and 26% free-cash-flow margin.
  • βœ“New products and segments could unlock additional revenue streams.
⚠️ Key Risks

Execution delays, intensifying competition, and valuation compression if growth decelerates.

APRE logo

APREA THERAPEUTICS INC

APRE
Financial Trends
RevenueThe total money the company brought in from sales, before subtracting any costs.
$0β–Ό βˆ’100.0% YoY
Gross MarginOf every $1 of sales, how much is left after the direct cost of making the product/service. Higher = more efficient.
-523.2%β–Ό βˆ’629.6% YoY
Operating IncomeProfit from the core business after operating costs, but before interest and taxes. Negative means the core business isn’t profitable yet.
βˆ’$13Mβ–Ό βˆ’7.6% YoY
Free Cash FlowCash left over after running the business and paying for equipment/capex. Negative means the company is burning cash.
βˆ’$13Mβ–Ό βˆ’5.0% YoY
Shares OutstandingHow many shares exist. Rising means the company is issuing more shares, which dilutes (shrinks) each existing owner’s slice.
7.7Mβ–² +29.1% YoY
Net CashCash minus total debt. Positive = more cash than debt (financially strong); negative = more debt than cash (net debt).
$15Mβ–Ό βˆ’$8M YoY
StockOtter Β· stockotter.space

About APREA THERAPEUTICS INC

Aprea Therapeutics, Inc. is a biopharmaceutical company in its clinical development stage, dedicated to discovering and marketing innovative cancer treatments. Their therapeutic approach centers on modulating DNA damage response pathways. The company's primary drug candidate, ATRN-119, is an oral ATR inhibitor currently undergoing Phase 1/2a clinical trials for patients with advanced solid tumors. Beyond this lead compound, Aprea's developmental pipeline includes ATRN-Backup, which is also an ATR inhibitor; ATRN-W1051, being explored for its anti-tumor effects; and ATRN-DDRi. Aprea Therapeutics, Inc. is headquartered in Boston, Massachusetts.

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Otter Score Breakdown

How it's scoredFive components, each rated 1–5β˜… and equally weighted (20%), averaged to a 0–100 score:πŸ’Ž Quality β€” gross marginπŸš€ Growth β€” revenue YoYβš–οΈ Valuation β€” P/S ratio⚑ Momentum β€” 30-day price changeπŸ’§ Dilution β€” 1-yr share issuance (buybacks score higher)
πŸ’ŽQualityβ˜…β˜…β˜…β˜…β˜…
πŸš€Growthβ˜…β˜…β˜…β˜…β˜…
βš–οΈValuationβ˜…β˜…β˜…β˜…β˜…
⚑Momentumβ˜…β˜…β˜…β˜…β˜…
πŸ’§Dilutionβ˜…β˜…β˜…β˜…β˜…
Overall Score
Weak
56/100

Analyst Ratings

β“˜
Consensus
Buy
10 analysts
Strong Buy4
Buy5
Hold1
Sell0
Strong Sell0
Ratings as of Sep 2026

Latest News & Updates

GlobeNewsWireΒ·7d ago

Aprea Therapeutics to Present Updated Interim Phase 1 Data on WEE1 Inhibitor APR-1051 in an Oral Presentation at 38th EORTC-NCI-AACR Symposium

DOYLESTOWN, Pa., Sept. 22, 2026 (GLOBE NEWSWIRE) -- Aprea Therapeutics, Inc. (Nasdaq: APRE) (β€œAprea”, or the β€œCompany”), a clinical-stage precision medicine oncology company focused on the discovery and development of ta

GlobeNewsWireΒ·19d ago

Aprea Therapeutics to Present at H.C. Wainwright 28th Annual Global Investment Conference

DOYLESTOWN, Pa., Sept. 10, 2026 (GLOBE NEWSWIRE) -- Aprea Therapeutics, Inc. (Nasdaq: APRE) (β€œAprea”, or the β€œCompany”), a clinical-stage precision medicine oncology company focused on the discovery and development of ta

GlobeNewsWireΒ·Aug 28

Aprea Therapeutics Announces Expansion of Intellectual Property Portfolio for Precision Oncology Programs

Company Strengthens Global Intellectual Property Portfolio with 28 Issued and 30 Pending Patents Company Strengthens Global Intellectual Property Portfolio with 28 Issued and 30 Pending Patents

GlobeNewsWireΒ·Aug 12

Aprea Therapeutics Announces Second Quarter 2026 Financial Results

Enrollment in the ongoing Phase 1 dose escalation ACESOT-1051 trial of oral WEE1 inhibitor APR-1051 is accelerating as dose escalation advances

PRNewsWireΒ·Aug 3

Lipocine Appoints Michael J. Grissinger to Board of Directors

SALT LAKE CITY, Aug. 3, 2026 /PRNewswire/ -- Lipocine Inc. (NASDAQ: LPCN), a biopharmaceutical company leveraging its proprietary technology platform to augment therapeutics through effective oral delivery, today announc

GlobeNewsWireΒ·Jul 30

Aprea Therapeutics Provides ACESOT-1051 Program Update for WEE1 Inhibitor APR-1051: Accelerating and Expanding Enrollment. Clinical Data Presentation Planned for Q4 2026

Next clinical data update from the ongoing Phase 1 dose escalation ACESOT-1051 trial anticipated at a medical meeting in Q4 2026, providing a near-term opportunity to demonstrate continued clinical progress with APR-1051