ANNX logo

ANNEXON INC

ANNXNASDAQ
πŸ† #2779 by market capEarnings Nov 9US Equity
$4.13β–² $0.12 (+2.99%)
πŸŒ™ After hours$4.20β–² 1.69%Regular close Β· extended-hours price shown
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24hβ–² 3.0%
7dβ–Ό 1.2%
14dβ–² 5.1%
30dβ–Ό 16.9%
ytdβ–Ό 17.6%
1yβ–² 32.8%
🏦Market Cap
$677M
Small Cap
πŸ“ˆRevenue Growth (YoY)
+0.0%
Slowing
πŸ“ŠGross Margin
0.0%
Thin
πŸ’΅FCF Margin
0.0%
Thin
βš–οΈP/S Ratio
0.0x
Cheap
Otter Score
72
Fair

Trading Snapshot

Day Range
$4.07 – $4.21
52-Week Range
$2.54 – $7.18
Volume
$2.13B
Avg Volume
$2.10B
Shares Outstanding
163.8M
Next Earnings
Oct 21, 2026

Fundamentals Snapshot

Annual Revenue
$133M
Last Q Revenue
$31M
P/E Ratio
-3.5
P/S Ratio
0.0x
EPS (TTM)
$-1.01
Dividend Yield
0.00%
Dilution (1yr)
+4.9%

Why Investors Own ANNX

  • βœ“High-growth profile β€” revenue up +2.4% YoY with expanding US Equity exposure.
  • βœ“Healthy economics β€” 64% gross margin and 20% free-cash-flow margin.
  • βœ“New products and segments could unlock additional revenue streams.
⚠️ Key Risks

Execution delays, intensifying competition, and valuation compression if growth decelerates.

ANNX logo

ANNEXON INC

ANNX
Financial Trends
RevenueThe total money the company brought in from sales, before subtracting any costs.
$0β–² +0.0% YoY
Operating IncomeProfit from the core business after operating costs, but before interest and taxes. Negative means the core business isn’t profitable yet.
βˆ’$216Mβ–² +40.5% YoY
Free Cash FlowCash left over after running the business and paying for equipment/capex. Negative means the company is burning cash.
βˆ’$186Mβ–² +58.0% YoY
Shares OutstandingHow many shares exist. Rising means the company is issuing more shares, which dilutes (shrinks) each existing owner’s slice.
155.1Mβ–² +4.9% YoY
Net CashCash minus total debt. Positive = more cash than debt (financially strong); negative = more debt than cash (net debt).
$136Mβ–² +$115M YoY
StockOtter Β· stockotter.space

About ANNEXON INC

Annexon, Inc. is a biopharmaceutical company currently engaged in clinical trials, dedicated to the discovery and advancement of therapies for a variety of autoimmune, neurodegenerative, and ophthalmic conditions. Central to its approach is the C1q molecule, which initiates the classical complement pathway. The company targets this pathway to address specific disease mechanisms, such as those seen in antibody-mediated autoimmune disorders and complement-driven neurodegeneration. The company's developmental pipeline features several promising candidates. ANX005, a monoclonal antibody, is in advanced clinical testing, undergoing Phase II/III trials for Guillain-BarrΓ© syndrome, as well as Phase II trials for warm autoimmune hemolytic anemia, Huntington's disease, and amyotrophic lateral sclerosis. Another candidate, ANX009, is currently in Phase Ib studies for lupus nephritis. Additionally, ANX007 is progressing through Phase II clinical trials for the treatment of geographic atrophy, an eye disease. Further investigational assets include ANX105, a monoclonal antibody being developed for neurodegenerative indications, and ANX1502, an oral small molecule under investigation for specific autoimmune conditions. Annexon, Inc. was established in 2011 and operates from its headquarters in Brisbane, California.

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Otter Score Breakdown

How it's scoredFive components, each rated 1–5β˜… and equally weighted (20%), averaged to a 0–100 score:πŸ’Ž Quality β€” gross marginπŸš€ Growth β€” revenue YoYβš–οΈ Valuation β€” P/S ratio⚑ Momentum β€” 30-day price changeπŸ’§ Dilution β€” 1-yr share issuance (buybacks score higher)
πŸ’ŽQualityβ˜…β˜…β˜…β˜…β˜…
πŸš€Growthβ˜…β˜…β˜…β˜…β˜…
βš–οΈValuationβ˜…β˜…β˜…β˜…β˜…
⚑Momentumβ˜…β˜…β˜…β˜…β˜…
πŸ’§Dilutionβ˜…β˜…β˜…β˜…β˜…
Overall Score
Fair
72/100

Analyst Price Target

β“˜
Average Target
$4.88
β–² +18.1% Upside
High Target$5.93
Low Target$3.85
Based on 36 analysts

Latest News & Updates

Seeking AlphaΒ·2d ago

Annexon: Preserving Patient Function Is The Real Investment Opportunity

Annexon targets functional patient outcomes in geographic atrophy and Guillain-BarrΓ© syndrome, aiming for clinical differentiation via vision and physical recovery preservation. ANNX maintains a cash runway into 2028, su

GlobeNewsWireΒ·5d ago

Annexon to Present Patient Baseline Characteristics from Vonaprument Phase 3 ARCHER II Pivotal Trial for Geographic Atrophy at The Retina Society 59th Annual Scientific Meeting

Oral Presentations Highlight Phase 2 Vision Protection and Enrollment of a Consistent Phase 3 Patient Population Well-Positioned to Replicate Phase 2 Vision Outcomes ARCHER II is the First Pivotal Trial Designed to Demon

GlobeNewsWireΒ·13d ago

Annexon Reports Inducement Grants to New Employees Under Nasdaq Listing Rule 5635(c)(4)

BRISBANE, Calif., Sept. 16, 2026 (GLOBE NEWSWIRE) -- Annexon, Inc. (Nasdaq: ANNX), a biopharmaceutical company advancing the next generation platform of targeted immunotherapies aimed at neuroinflammatory diseases that i

GlobeNewsWireΒ·27d ago

Annexon to Participate in Upcoming September Investor Conferences

BRISBANE, Calif., Sept. 02, 2026 (GLOBE NEWSWIRE) -- Annexon, Inc.Β (Nasdaq: ANNX), a biopharmaceutical company advancing the next generation platform of targeted immunotherapies aimed at neuroinflammatory diseases that i

Seeking AlphaΒ·Aug 12

Annexon, Inc. (ANNX) Q2 2026 Earnings Call Transcript

Annexon, Inc. (ANNX) Q2 2026 Earnings Call Transcript

MarketBeatΒ·Aug 12

Annexon Q2 Earnings Call Highlights

Annexon NASDAQ: ANNX said it expanded its pivotal ARCHER II trial of vonaprument in geographic atrophy, adding an independent 24-month dual primary endpoint alongside the study's existing 15-month primary endpoint. The c